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Auto-Tube Compensation (ATC) on the Dräger E-2 Ventilator Reduces Work of Breathing (WOB) During CPAP



RH Kallet MS RRT, M Siobal BS RRT, RW Kraemer CRTT, J Tang MD
Respiratory Care Services, Department of Anesthesia, San Francisco General Hospital, University of California San Francisco.


Background: ATC augments ventilator inspiratory flow rate [I to achieve the proximal airway pressure target at the distal tip of the endotracheal tube (ETT), thus counterbalancing the imposed WOB of the artificial airway. ATC can be set to compensate for a variable percentage of tube resistance. We investigated the effects of 3 levels of ATC on WOB as ETT size was varied.

Methods: A standard WOB lung model was constructed using a Michigan Instruments TTL set at a compliance of 27 mL/cm H2O; powered by a Veolar ventilator set to create a VT demand of 500 mL at a respiratory rate of 24 and a peak [I demand of 50 L/m. The Dräger E-2 treatment ventilator was set at CPAP of 5 cm H2O and a flow trigger of 5 L/min. We measured WOB performed by the Dräger E-2 ventilator (WOBv) and WOB performed by the drive ventilator to displace the ?patient? compartment (WOBc). WOBc approximated the total imposed WOB (ETT + circuit). Experiments were conducted with ATC turned off and at an ATC of 100%, 75% and 50% compensation set to the corresponding ET size used in the model (8.0 and 6.0 mm ID). Measurements were made with a BICORE CP-100 monitor and 10 breaths were used for analysis. Data was analyzed using repeated-measures analysis of variance (ANOVA) and Tukey-Kramer tests. Alpha was set at 0.05.

Results: At all levels of ATC, WOBc was significantly reduced compared to CPAP without ATC. The ability to reduce WOB diminished as the ATC level was lowered to 50%. Also, ATC 100% was not as effective in reducing WOBc as ETT size decreased (45% vs. 26% at 8.0 and 6.0 ETT size respectively). All comparisons were statistically significant.

ETT 8.0 WOBc (J/L) WOBv (J/L) [I (L/m) VT (mL)
ATC OFF 0.69 ± .01 0.23 ± .003 68 ± 1 563 ± 5
ATC 100% 0.38 ± .02 0.99 ± .03 91 ± 2 572 ± 6
ATC 75% 0.42 ± .02 0.73 ± .01 82± 1 569 ± 3
ATC 50% 0.49± .01 0.53 ± .01 77 ± 1 575 ± 5
ETT 6.0
ATC OFF 1.45 ±.02 0.28 ± .004 54 ± 0.7 552 ± 4
ATC 100% 1.07 ± .01 1.06 ± .01 64 ± 0.7 589 ± 3
ATC 75% 1.18 ± .02 0.83 ±.004 61 ± .07 580 ± 0
ATC 50% 1.28 ± .01 0.61 ± .005 58 ± .04 570 ± 0

Conclusion: ATC reduced total imposed WOB by increasing peak delivery above flow demand and probably should be used at 100% compensation. However, ATC?s effectiveness appears to be diminished by the presence of a small ETT size

OF-01-196
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