| Symptom |
Irritation |
Type
I |
Type
IV |
| Timing of onset |
Minutes to hours |
Minutes to 1 hour |
1-2 days |
| Sensory description |
Pain, burning, stinging,
discomfort, exceeding itching |
Itching, tingling |
Itching first, continuing
to pain as skin breaks down |
| % of population reacting |
Large percent |
Small percent, except
in special cases |
Small percent |
| Appearance |
Redness, crusting,
skin thickens, swells, fissures, scabbing sores, drying, papules,
peeling |
Pink raised areas,
hives often blanched in the center, swelling |
Redness, crusting,
thickening of skin, swelling, papules, drying, peeling, vesicles |
| Fissures or papules |
Prone to fissures |
No fissures or papules |
Sores not fissures |
| Appearance of skin
touching latex |
Glazed, parched, scalded
appearance |
Tight due to swelling,
no dryness |
Dry and crusted |
| Healing (unoccluded) |
Follows substance removal
(0-2 weeks) |
Condition diminishes
within hours of glove abstinence |
Condition may not diminish
after glove abstinence (but may within 1-2 weeks) |
| History of allergies |
General population
mix |
Most reactors have
a history of allergies |
Most reactors have
a history of allergies |
| Boundaries of the reaction |
Sharp, definite, may
show border of gown cuff under glove |
Undefined, may be under
glove or whole body |
Undefined, may be under
glove or move up the arm |
| Tendency to spread |
No, inflammation limited
to glove contact area |
Yes, may spread beyond
glove contact areas |
Yes, may spread beyond
glove contact areas |
| Respiratory involvement |
None |
Wheezing, runny nose,
difficulty breathing |
None |
| Facial involvement |
Possible only by contacting
face with glove irritant |
Swelling of eyelids,
lips, face, tearing, itchy eyes |
None |
| Systemic involvement |
None |
Nausea, abdominal cramps,
rapid heart rate, hives, dyspnea, hypertension, shock |
None |
| How acquired |
Skin contact |
Skin, mucous membrane,
or open wound contact, injection aspiration |
Skin contact |
