Gloves with Neu-TheraT formula were subjected to an extensive series of controlled, qualitative and
quantitative studies performed at the California Skin Research Institute, a division of DermTech
International, and overseen by a board-certified dermatologist.
The test group consisted of health-care professionals with compromised skin who typically wore gloves as part
of their daily routine: registered nurses, surgical technicians and other operating room personnel, and physical
and occupational therapists.
Quantitative test methods used included the following personal-care product industry standards:
Testing demonstrated a significant, measurable improvement in the skin of the clinicians
who participated in the study.
Key dermatological measures of skin health and damage Various physical properties of the skin are important
in the development of an irritant skin response. The
following noninvasive measuring methods have been
used to investigate these properties and assess the
health or degree of damage to the skin:
Trans-evaporative water loss (TEWL)
The passive diffusion of water loss through the stratum
corneum relates directly to skin integrity. In other words,
compromised skin tends to lose more moisture than
normal skin. Using an evaporimeter, which records the
total water evaporation from the skin, the TEWL test
measures the integrity of the stratum corneum when
relative humidity, temperature and sweating are
controlled. A number of studies have demonstrated
that the skin's TEWL values are significantly increased
after irritant exposure.x
Electrical conductance The moisture content (hydration state) of normal skin
is significantly decreased, and the response to irritants
and occurrence of skin irritation are increased during
the winter months.xi Various electrical methods can
be used to measure changes in skin hydration.
Colorimetry Changes in erythema (redness) correlate well with
visually scored skin damage. A chromameter is a
colorimeter used to quantify differences in skin redness.
Firmness and elasticity The skin's viscoelasticity (e.g., stickiness and stretchiness)
is due to its collagen and elastin fibers. The stratum
corneum must be intact and flexible to function
effectively. When the stratum corneum is damaged,
it becomes dry, tight and inelastic. At its worst, it is
cracked, providing avenues for infection. The Cutometer®
instrument operates a suction perpendicular to the
skin surface to measure the amount of deformation
of the skin. This measure can then be related to the
firmness and elasticity of the skin.
D-squames® tapes
D-squames® tape disks are constructed from a clear
grade of polyester support film and a super-clear
adhesive. They are used to sample the outer dead skin
layers. The disk is analyzed by determining the size of
the dead cells (fine, medium or coarse). The finer the
cells are, the more moist the skin. Damaged skin sheds
and flakes more than normal skin.
Gloves with Neu-TheraT formula were subjected to an extensive series of controlled, qualitative and
quantitative studies performed at the California Skin Research Institute, a division of DermTech
International, and overseen by a board-certified dermatologist.
Colorimetry
D-squames® tapes